Methotrexate treatment for type 1 (reversal) leprosy reactions.
نویسندگان
چکیده
Corticosteroids are the drugs of choice for treatment of type 1 leprosy reactions, but when these agents cannot be used because of their adverse effects, alternative treatments are needed. We report the first case, to our knowledge, of a type 1 leprosy reaction that was successfully treated with methotrexate in a patient intolerant to corticosteroids who had borderline lepromatous leprosy.
منابع مشابه
Diagnosis and treatment of leprosy type 1 (reversal) reaction.
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Leprosy is a chronic disease caused by Mycobacterium leprae. Its course is complicated by acute onset of inflammatory reactions which can occur before, during and after treatment of the disease. The reactions are classified as Type 1 reaction or reversal reaction and Type 2 reaction or erythema nodosum leprosum (ENL). Reversal reaction is a Type IV delayed type hypersensitivity reaction while e...
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ورودعنوان ژورنال:
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
دوره 45 1 شماره
صفحات -
تاریخ انتشار 2007